BDBM50366914 CHEMBL1788221

SMILES CN(C)CCNC(=O)C1=C[C@@]2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3F)cc1)c1ccccc1C2

InChI Key InChIKey=OFQCVYOFPPDYDD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50366914   

TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366914(CHEMBL1788221)
Affinity DataIC50: 4nMAssay Description:Evaluated for intracellular calcium mobilization in HEK- 293 cells transfected to express human vasopressin V1a receptor (Compound 7o)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366914(CHEMBL1788221)
Affinity DataIC50: 78nMAssay Description:Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366914(CHEMBL1788221)
Affinity DataIC50: 341nMAssay Description:Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Rat)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366914(CHEMBL1788221)
Affinity DataIC50: 433nMAssay Description:Evaluated for binding affinity towards vasopressin receptor V1a in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366914(CHEMBL1788221)
Affinity DataIC50: 444nMAssay Description:Evaluated for binding affinity towards vasopressin V2 receptor in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366914(CHEMBL1788221)
Affinity DataIC50: 646nMAssay Description:Evaluated for accumulation of cAMP in transfected HEK293 cells expressing human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed