BDBM50370827 CHEMBL374569::US12377086, Compound 45

SMILES OC(=O)c1ccc2cccnc2c1O

InChI Key InChIKey=JYIAZVFJRYLCBH-UHFFFAOYSA-N

Data  2 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50370827   

TargetEgl nine homolog 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human EGLN1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataEC50: >2.50E+5nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)
TBA

US Patent
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataIC50: 740nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2025
Entry Details
Go to US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)
TBA

US Patent
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataIC50: 760nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2025
Entry Details
Go to US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)
TBA

US Patent
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataKi:  280nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2025
Entry Details
Go to US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)
TBA

US Patent
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataKi:  350nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2025
Entry Details
Go to US Patent