BDBM50371413 CHEMBL270959

SMILES Nc1ccc(cc1C(=O)NCC(=O)N[C@H]1CCCC[C@H]1NC(=O)c1ccc(cc1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=OVHPQIOWPGMWFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50371413   

TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371413(CHEMBL270959)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human CCR2 in PBMCs assessed as inhibition of MCP1-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371413(CHEMBL270959)
Affinity DataIC50: 23nMAssay Description:Displacement of radiolabeled MCP1 from human CCR2 in PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371413(CHEMBL270959)
Affinity DataIC50: 63nMAssay Description:Antagonist activity at human CCR2 in PBMCs assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed