BDBM50371414 CHEMBL271828

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)CNC(=O)c1cc(ccc1NC(=O)C1CCCCC1)C(F)(F)F

InChI Key InChIKey=VZVLCXRPEZHWGK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50371414   

TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371414(CHEMBL271828)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human CCR2 in PBMCs assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371414(CHEMBL271828)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at human CCR2 in PBMCs assessed as inhibition of MCP1-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371414(CHEMBL271828)
Affinity DataIC50: 9nMAssay Description:Displacement of radiolabeled MCP1 from human CCR2 in PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed