BDBM50371564 CHEMBL403991

SMILES CCS(=O)(=O)C=C[C@H](CCc1ccccc1)NC(=O)CN1c2ccccc2C(=N[C@H](COC(=O)Nc2ccc(Cl)cc2C(F)(F)F)C1=O)c1ccccc1

InChI Key InChIKey=SQGORGFXCWFDEK-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50371564   

TargetFalcipain 2(malaria parasite P. falciparum)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50371564(CHEMBL403991)
Affinity DataKi:  320nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50371564(CHEMBL403991)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50371564(CHEMBL403991)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50371564(CHEMBL403991)
Affinity DataKi:  1.35E+4nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed