BDBM50371596 CHEMBL1162163

SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c(NC(=O)Nc3ccccc3)ncnc12

InChI Key InChIKey=NPEOZNAZFLOGJY-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50371596   

TargetP2Y purinoceptor 1(Human)
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371596(CHEMBL1162163)
Affinity DataEC50:  2.63E+3nMAssay Description:Agonist at human recombinant P2Y1 receptor expressed in human 1321 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 2(Human)
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371596(CHEMBL1162163)
Affinity DataEC50:  9.40E+3nMAssay Description:Agonist activity at P2Y2 receptor expressed in human 1321 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371596(CHEMBL1162163)
Affinity DataEC50:  9.75E+3nMAssay Description:Agonist activity at P2Y6 receptor expressed in human 1321 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371596(CHEMBL1162163)
Affinity DataIC50: 1.08E+4nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed