BDBM50371621 CHEMBL438889

SMILES CNCc1cc(ccc1Oc1ccc(Cl)cc1Cl)N1CCCS1(=O)=O

InChI Key InChIKey=YZHPFFVLNPTVQU-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50371621   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50371621(CHEMBL438889)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]5HT uptake at human 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50371621(CHEMBL438889)
Affinity DataIC50: 17nMAssay Description:Inhibition of [3H]NA uptake at human NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50371621(CHEMBL438889)
Affinity DataIC50: 138nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50371621(CHEMBL438889)
Affinity DataKi:  1.56E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed