BDBM50372526 CHEMBL261646

SMILES CN(C1CCN(CC1)c1ccnc(C)c1)C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1

InChI Key InChIKey=HPHLSPULJKIGAN-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50372526   

TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataKi:  15nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataIC50: 61nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataIC50: 61nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataKi:  6.70E+4nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed