BDBM50372583 CHEMBL258056

SMILES OC1CCc2c(Cl)ccc(Nc3cc(ncn3)-c3ccc(cc3)C(F)(F)F)c2C1

InChI Key InChIKey=DJTKBJVKWXYQKY-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372583   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Amgen

Curated by ChEMBL

LigandBDBM50372583(CHEMBL258056)Copy SMILESCopy InChI

Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium mobilizationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/15/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Amgen

Curated by ChEMBL

LigandBDBM50372583(CHEMBL258056)Copy SMILESCopy InChI

Affinity DataIC50: 5.60nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium mobilizationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/15/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL