BDBM50372586 CHEMBL255420

SMILES Oc1ccc2cccc(Nc3cc(ncn3)-c3ccc(cc3)C(F)(F)F)c2c1

InChI Key InChIKey=HXKPZQRDFRBMGH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372586   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Amgen

Curated by ChEMBL

LigandBDBM50372586(CHEMBL255420)Copy SMILESCopy InChI

Affinity DataIC50: 0.650nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium mobilizationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/15/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Amgen

Curated by ChEMBL

LigandBDBM50372586(CHEMBL255420)Copy SMILESCopy InChI

Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium mobilizationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/15/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL