BDBM50374292 CHEMBL208566

SMILES CCC[C@H](NC(=O)C1(CCCCC1)NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)c1nnc(o1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=TYUNJJSHOCWVMW-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50374292   

TargetCathepsin K(Human)
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50374292(CHEMBL208566)
Affinity DataKi:  54nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCathepsin K(Human)
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50374292(CHEMBL208566)
Affinity DataKi:  54nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374292(CHEMBL208566)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374292(CHEMBL208566)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50374292(CHEMBL208566)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50374292(CHEMBL208566)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374292(CHEMBL208566)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374292(CHEMBL208566)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed