BDBM50374481 CHEMBL257092

SMILES Cc1ccccc1N=C(NC#N)N1CCN(C(C1)c1ccccc1)C(=O)Cc1ccsc1

InChI Key InChIKey=DOBQBATWARGAHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374481   

TargetP2X purinoceptor 7(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50374481(CHEMBL257092)
Affinity DataIC50: 71nMAssay Description:Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50374481(CHEMBL257092)
Affinity DataIC50: 270nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed