BDBM50375122 CHEMBL427833

SMILES CN(CCCn1c2c(Cl)cccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)c1cccc2cccnc12

InChI Key InChIKey=XYQSDKPJILDTCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375122   

TargetC-X-C chemokine receptor type 3(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375122(CHEMBL427833)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]-CXCL10 from human CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375122(CHEMBL427833)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cell membrane assessed as inhibition of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Mouse)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375122(CHEMBL427833)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]-CXCL10 from mouse CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed