BDBM50375355 CHEMBL260861

SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1

InChI Key InChIKey=HVKVREKLPAMYHA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50375355   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50375355(CHEMBL260861)
Affinity DataIC50: 3nMAssay Description:Inhibition of human cSrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50375355(CHEMBL260861)
Affinity DataIC50: 7nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50375355(CHEMBL260861)
Affinity DataIC50: 100nMAssay Description:Inhibition of human cSrc in COS7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50375355(CHEMBL260861)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50375355(CHEMBL260861)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ZAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50375355(CHEMBL260861)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50375355(CHEMBL260861)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50375355(CHEMBL260861)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed