BDBM50375675 CHEMBL270545

SMILES COc1cc2nccc(Oc3ccc4N(CCOc4c3)C(=O)NC(C)C)c2cc1OC

InChI Key InChIKey=OZHHLHNBHBGTSP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50375675   

TargetVascular endothelial growth factor receptor 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50375675(CHEMBL270545)
Affinity DataIC50: 39.8nMAssay Description:Inhibition of human VEGFR2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50375675(CHEMBL270545)
Affinity DataIC50: 40nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50375675(CHEMBL270545)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50375675(CHEMBL270545)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50375675(CHEMBL270545)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed