BDBM50375680 CHEMBL270550

SMILES COc1cc2nccc(Oc3ccc4N(CCOc4c3)C(=O)Nc3ccccc3Cl)c2cc1OC

InChI Key InChIKey=ZDNWBLXKFNBSDR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50375680   

LigandPNGBDBM50375680(CHEMBL270550)
Affinity DataIC50: 19nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50375680(CHEMBL270550)
Affinity DataIC50: 19.1nMAssay Description:Inhibition of human VEGFR2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50375680(CHEMBL270550)
Affinity DataIC50: 290nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50375680(CHEMBL270550)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50375680(CHEMBL270550)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed