BDBM50375741 CHEMBL272331

SMILES COc1cc(CN2CC[C@H](C2)NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)ccc1O

InChI Key InChIKey=MLYWTGAAWAAAKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50375741   

TargetC-C chemokine receptor type 2(Human)
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandPNGBDBM50375741(CHEMBL272331)
Affinity DataIC50: 77nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandPNGBDBM50375741(CHEMBL272331)
Affinity DataIC50: 153nMAssay Description:Displacement of [125I]MCP1 from human CCR2b in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed