BDBM50376817 CHEMBL259643

SMILES CCN(C1CCCc2nc(cc(OC)c12)-c1ccccc1CC)c1cccc2ccccc12

InChI Key InChIKey=MMXMFMPXNVWWPU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376817   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50376817(CHEMBL259643)
Affinity DataKi:  86nMAssay Description:Displacement of [125I]C5a from human C5a receptor in U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50376817(CHEMBL259643)
Affinity DataIC50: 650nMAssay Description:Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed