BDBM50377192 CHEMBL428252

SMILES CC1CN(CCCNC(=O)c2nc(no2)-c2ccncc2)CCN1c1cccc(C)c1

InChI Key InChIKey=AKPOETSCZOWHEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377192   

TargetGlycogen synthase kinase-3 beta(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50377192(CHEMBL428252)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of GSK3-beta assessed as breakdown of glycogen synthase derived substrate peptide by ADP hunter assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50377192(CHEMBL428252)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GSK3-beta assessed as beta-casein level by RKO-cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed