BDBM50377205 CHEMBL254582

SMILES CC1CN(CCN1CCCNC(=O)c1nc(no1)-c1cccnc1)c1cccc(C)c1

InChI Key InChIKey=LBCGZHCUSUIQSD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50377205   

TargetGlycogen synthase kinase-3 beta(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50377205(CHEMBL254582)
Affinity DataIC50: 200nMAssay Description:Inhibition of GSK3-beta by ATP-based competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50377205(CHEMBL254582)
Affinity DataIC50: 690nMAssay Description:Inhibition of GSK3-beta assessed as breakdown of glycogen synthase derived substrate peptide by ADP hunter assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50377205(CHEMBL254582)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of GSK3-beta assessed as beta-casein level by RKO-cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed