BDBM50377357 CHEMBL258694

SMILES CC(C)c1c(cn2ncnc(Nc3cnc4[nH]ccc4c3)c12)-c1nnc(C)o1

InChI Key InChIKey=LQNDDQQRHZEHDD-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50377357   

TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50377357(CHEMBL258694)
Affinity DataIC50: 31nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50377357(CHEMBL258694)
Affinity DataIC50: 61nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50377357(CHEMBL258694)
Affinity DataIC50: 150nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50377357(CHEMBL258694)
Affinity DataIC50: 185nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50377357(CHEMBL258694)
Affinity DataIC50: 389nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50377357(CHEMBL258694)
Affinity DataIC50: 500nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50377357(CHEMBL258694)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50377357(CHEMBL258694)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50377357(CHEMBL258694)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed