BDBM50377767 CHEMBL429498

SMILES Clc1ccc(CC(=O)Nc2cccc(c2)-c2[nH]c(nc2-c2ccnc(NCCN3CCNC3=O)n2)C2CC2)cc1

InChI Key InChIKey=CBZHOVUXXVXVNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377767   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377767(CHEMBL429498)
Affinity DataIC50: 1nMAssay Description:Inhibition of C-RAF kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377767(CHEMBL429498)
Affinity DataIC50: 7nMAssay Description:Inhibition of B-RAF kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed