BDBM50377842 CHEMBL259083

SMILES O[C@H](CNCc1cccc(OC(F)(F)F)c1)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(Cc2ccccc2)C(=O)N1

InChI Key InChIKey=ALDJXOMRVJRQQK-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50377842   

TargetCathepsin D(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377842(CHEMBL259083)
Affinity DataKi:  300nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377842(CHEMBL259083)
Affinity DataKi:  1.88E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377842(CHEMBL259083)
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of human BACE1 by SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed