BDBM50377860 CHEMBL411917

SMILES CC(C)c1cccc(CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CN(Cc3cc(F)cc(F)c3)C(=O)N2)c1

InChI Key InChIKey=DIVOTBMEMUKMAL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50377860   

TargetBeta-secretase 1(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377860(CHEMBL411917)
Affinity DataKi:  18nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCathepsin D(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377860(CHEMBL411917)
Affinity DataKi:  151nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377860(CHEMBL411917)
Affinity DataIC50: 580nMAssay Description:Inhibition of human BACE1 by SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed