BDBM50377949 CHEMBL476751

SMILES CC(C)c1c(Sc2ccc(CC(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2)[nH]c2nc(N)nc(N)c12

InChI Key InChIKey=VITYIWQPGWVLBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377949   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50377949(CHEMBL476751)
Affinity DataIC50: 186nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed