BDBM50378005 CHEMBL1627317::US8748608, 43

SMILES COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3ccccc3o2)CC1

InChI Key InChIKey=JCJRRQWOAHHCRM-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50378005   

TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandPNGBDBM50378005(CHEMBL1627317 | US8748608, 43)
Affinity DataKi:  5.40nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandPNGBDBM50378005(CHEMBL1627317 | US8748608, 43)
Affinity DataKi:  7.51nMAssay Description:Displacement of [125]IABN from human D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50378005(CHEMBL1627317 | US8748608, 43)
Affinity DataKi:  2.14E+3nMAssay Description:Displacement of [125]IABN from human D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50378005(CHEMBL1627317 | US8748608, 43)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandPNGBDBM50378005(CHEMBL1627317 | US8748608, 43)
Affinity DataIC50:  11.2nMAssay Description:Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed