BDBM50378006 CHEMBL1627316::US8748608, 42

SMILES OC(CCNC(=O)c1cc2ccccc2o1)CN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key InChIKey=DMQIMKFFQYYLKW-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50378006   

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378006BDBM50378006(CHEMBL1627316 | US8748608, 42)
Affinity DataKi:  0.980nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378006BDBM50378006(CHEMBL1627316 | US8748608, 42)
Affinity DataKi:  6.11nMAssay Description:Displacement of [125]IABN from human D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378006BDBM50378006(CHEMBL1627316 | US8748608, 42)
Affinity DataIC50: 13.7nMAssay Description:Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378006BDBM50378006(CHEMBL1627316 | US8748608, 42)
Affinity DataEC50:  22.8nMAssay Description:Agonist activity at human D3 receptor expressed in HEK293 cells assessed as stimulation of mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378006BDBM50378006(CHEMBL1627316 | US8748608, 42)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125]IABN from human D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378006BDBM50378006(CHEMBL1627316 | US8748608, 42)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed