BDBM50378394 CHEMBL4161022
SMILES CO[C@H]1C[C@H](C1)n1c2c(cnc3cc(F)c(cc23)-c2ccc(NC(=O)CCCN(C)C)nc2)n(C)c1=O
InChI Key InChIKey=WYMFQMUBKZKGGQ-HDICACEKSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50378394
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ATR in human HT29 cells assessed as decrease in Chk1 phosphorylation at Ser 345 preincubated for 1 hr followed by 4NQO addition and mea...More data for this Ligand-Target Pair