BDBM50378951 CHEMBL2011434::US9394290, 39
SMILES C(c1ccc(nc1)-c1ccco1)n1ccnc1
InChI Key InChIKey=KXXPEQYOMQDBDO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50378951
TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 167nMT: 37°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 167nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.16E+3nMT: 37°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair