BDBM50378961 CHEMBL2011243::US9394290, 6

SMILES Clc1ncc(Cn2ccnc2)cc1Br

InChI Key InChIKey=QHUNWISICRWPTM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378961   

TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM50378961(CHEMBL2011243 | US9394290, 6)
Affinity DataIC50: 168nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM50378961(CHEMBL2011243 | US9394290, 6)
Affinity DataIC50: 168nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM50378961(CHEMBL2011243 | US9394290, 6)
Affinity DataIC50: 576nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM50378961(CHEMBL2011243 | US9394290, 6)
Affinity DataIC50: 576nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed