BDBM50379136 CHEMBL2012811

SMILES CC(C)C[C@H]1CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCCC(=O)C(F)(F)F)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N1

InChI Key InChIKey=WTXFMLFPFKCMHO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50379136   

TargetHistone deacetylase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50379136(CHEMBL2012811)
Affinity DataIC50: 32nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2020
Entry Details Article
PubMed
LigandPNGBDBM50379136(CHEMBL2012811)
Affinity DataIC50: 62nMAssay Description:Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50379136(CHEMBL2012811)
Affinity DataIC50: 62nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50379136(CHEMBL2012811)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50379136(CHEMBL2012811)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of HDAC6 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed