BDBM50379162 CHEMBL2010850

SMILES CN([C@@H]1CCN(Cc2nc3cc(F)ccc3s2)C[C@@H]1F)C(=O)Cc1ccc(cc1)-n1cnnn1

InChI Key InChIKey=ULFXUVFXHTYAIU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379162   

TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50379162(CHEMBL2010850)Copy SMILESCopy InChI

Affinity DataEC50:  12nMAssay Description:Agonist activity at human GPR119 receptor expressed in HEK293 cells assessed as cAMP accumulation after 45 mins by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50379162(CHEMBL2010850)Copy SMILESCopy InChI

Affinity DataIC50: 4.70E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL