BDBM50379389 CHEMBL2010816

SMILES Nc1cncc(Nc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1

InChI Key InChIKey=YBPKUYHMTYRITD-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50379389   

LigandPNGBDBM50379389(CHEMBL2010816)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379389(CHEMBL2010816)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by manual whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379389(CHEMBL2010816)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379389(CHEMBL2010816)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by manual whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379389(CHEMBL2010816)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human non-inactivated NaV 1.7 channel expressed in HEK293 cells by manual whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379389(CHEMBL2010816)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human ERG by PatchXpress voltage patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379389(CHEMBL2010816)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human non-inactivated NaV 1.5 channel expressed in HEK293 cells by manual whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50379389(CHEMBL2010816)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50379389(CHEMBL2010816)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed