BDBM50379398 CHEMBL2011952

SMILES Nc1nccc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1

InChI Key InChIKey=QXBHEAFYUAPEIF-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379398   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Amgen

Curated by ChEMBL

LigandBDBM50379398(CHEMBL2011952)Copy SMILESCopy InChI

Affinity DataKi:  320nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetSodium channel protein type 9 subunit alpha(Human)
Amgen

Curated by ChEMBL

LigandBDBM50379398(CHEMBL2011952)Copy SMILESCopy InChI

Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL