BDBM50379427 CHEMBL2012044

SMILES Nc1cncc(Nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)n1

InChI Key InChIKey=PMMALHFQLZXMOO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50379427   

LigandPNGBDBM50379427(CHEMBL2012044)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379427(CHEMBL2012044)
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379427(CHEMBL2012044)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed