BDBM50379534 CHEMBL2012837

SMILES CCC(NCCCC[C@@H](Oc1cc(C)c(F)c(C)c1)C(=O)NO)c1ccc(F)cc1

InChI Key InChIKey=AWFIZJRPXRHSEA-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50379534   

TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandPNGBDBM50379534(CHEMBL2012837)
Affinity DataKi:  1nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Panthera Biopharma

Curated by ChEMBL
LigandPNGBDBM50379534(CHEMBL2012837)
Affinity DataIC50: 340nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Panthera Biopharma

Curated by ChEMBL
LigandPNGBDBM50379534(CHEMBL2012837)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Panthera Biopharma

Curated by ChEMBL
LigandPNGBDBM50379534(CHEMBL2012837)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP-12 using OmniMMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Panthera Biopharma

Curated by ChEMBL
LigandPNGBDBM50379534(CHEMBL2012837)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP-3 using OmniMMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Panthera Biopharma

Curated by ChEMBL
LigandPNGBDBM50379534(CHEMBL2012837)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP-9 using OmniMMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Panthera Biopharma

Curated by ChEMBL
LigandPNGBDBM50379534(CHEMBL2012837)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP-1 using OmniMMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Panthera Biopharma

Curated by ChEMBL
LigandPNGBDBM50379534(CHEMBL2012837)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP-14 using OmniMMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed