BDBM50380048 CHEMBL2012629

SMILES OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)C(=O)Nc1nnc(Cc2ccccc2F)s1

InChI Key InChIKey=DBKHBTHNEDTXCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380048   

TargetDiacylglycerol O-acyltransferase 1(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50380048(CHEMBL2012629)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant DGAT1 in Chang cells using [14C]-glycerol as substrate assessed as decrease in triglycerides synthesis after 6 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50380048(CHEMBL2012629)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed