BDBM50380092 CHEMBL2012918

SMILES Nc1ncc(Cn2cc(CN3CCN(CC3)c3nc4n(cc(C(O)=O)c(=O)c4cc3F)C3CC3)nn2)c(N)n1

InChI Key InChIKey=ZIHDURDKUXKORD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380092   

TargetDihydrofolate reductase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50380092(CHEMBL2012918)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed