BDBM50380093 CHEMBL2012917

SMILES OC(=O)c1cn(C2CC2)c2nc(N3CCN(CC#C)CC3)c(F)cc2c1=O

InChI Key InChIKey=FHUXSSIKFSRGNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380093   

TargetDihydrofolate reductase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50380093(CHEMBL2012917)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed