BDBM50380370 CHEMBL2017969

SMILES Nc1ncc(-c2cc(Nc3cnc4ccccc4c3)nc(n2)N2CCOCC2)c(=O)[nH]1

InChI Key InChIKey=UVQOEYYQNJINOI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380370   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50380370(CHEMBL2017969)Copy SMILESCopy InChI

Affinity DataIC50:  7.40nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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