BDBM50380458 CHEMBL2018752

SMILES CCOC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1Cl

InChI Key InChIKey=WMWSTVYFFWEFCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380458   

TargetVascular endothelial growth factor receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50380458(CHEMBL2018752)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50380458(CHEMBL2018752)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human EGFR expressed in human A431 cells using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed