BDBM50380485 CHEMBL2018882

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c2cc1OC

InChI Key InChIKey=SHKVYTQIJOOEMA-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50380485   

TargetPlatelet-derived growth factor receptor beta(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDGFR-beta (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 9nMAssay Description:Inhibition of VEGFR3 (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 16nMAssay Description:Inhibition of c-Kit (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 46nMAssay Description:Inhibition of VEGFR1 (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 930nMAssay Description:Inhibition of Raf (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of c-MET (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 5.47E+3nMAssay Description:Inhibition of Src (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR expressed in human A431 cells using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50380485(CHEMBL2018882)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR after 1 hr using [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed