BDBM50380486 CHEMBL2018883

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(Br)cc4)c(C)c3)c2cc1OC

InChI Key InChIKey=WLLFXZUEWKSPOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380486   

TargetVascular endothelial growth factor receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50380486(CHEMBL2018883)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50380486(CHEMBL2018883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR expressed in human A431 cells using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed