BDBM50380616 CHEMBL2016869
SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2Cc3cccc(CNC(=O)CN4CCN(CC4)CC(=O)NCc4cccc(C[C@@H](NS(=O)(=O)Cc5ccccc5)C(=O)N2)c4)c3)cc1
InChI Key InChIKey=UPFBONOEYAFXQG-QPPIDDCLSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50380616
Affinity DataKi: 4.10nMAssay Description:Inhibition of plasmin by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Inhibition of thrombin by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of factor 10a by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 25.3nMAssay Description:Inhibition of plasma kallikrein by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 26.3nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 31.6nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Inhibition of activated protein C by dixon plot methodMore data for this Ligand-Target Pair