BDBM50381159 CHEMBL2018217

SMILES CC1CN(CCO1)c1cc(=O)n2nc(C)n(Cc3cccc(Cl)c3Cl)c2n1

InChI Key InChIKey=XAWLMFFLUSASPB-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50381159   

LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 250nMAssay Description:Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 250nMAssay Description:Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 320nMAssay Description:Inhibition of PI3Kalpha by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 320nMAssay Description:Inhibition of PI3Kalpha by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 500nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PI3Kalpha by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed