BDBM50381656 CHEMBL2022296

SMILES COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)C(=O)c1cccc(c1)C(N)=O

InChI Key InChIKey=IFWPDDCHZMBABO-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50381656   

TargetKappa-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50381656(CHEMBL2022296)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50381656(CHEMBL2022296)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as calcium mobilization after 1 hrs by fluorescence analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50381656(CHEMBL2022296)
Affinity DataEC50:  730nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as [35S]GTP-gamma-S binding after 3 hrs by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50381656(CHEMBL2022296)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50381656(CHEMBL2022296)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed