BDBM50381816 CHEMBL2023642

SMILES OC(=O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccncc3)cc2)c2ccccc12

InChI Key InChIKey=XTBQBHZMXVRFPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50381816   

TargetProstaglandin D2 receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50381816(CHEMBL2023642)
Affinity DataIC50: 83nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50381816(CHEMBL2023642)
Affinity DataIC50: 83nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50381816(CHEMBL2023642)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human CRTH2 transfected in human KB8 cells assessed as inhibition of PGD2-induced increase in intracellular Ca2+ by fluo-4AM d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed