BDBM50381822 CHEMBL2023648

SMILES COc1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)c1ncc(CC(O)=O)c2ccccc12

InChI Key InChIKey=WTEPZSQKRLXTSG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50381822   

TargetProstaglandin D2 receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50381822(CHEMBL2023648)
Affinity DataIC50: 7.30nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50381822(CHEMBL2023648)
Affinity DataIC50: 7.30nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50381822(CHEMBL2023648)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human CRTH2 transfected in human KB8 cells assessed as inhibition of PGD2-induced increase in intracellular Ca2+ by fluo-4AM d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed