BDBM50382648 CHEMBL2024001

SMILES COc1cc(Nc2nccc(n2)N2CCC[C@@H](C2)C(=O)NCc2cccc(c2)N2CCOCC2)cc(OC)c1OC

InChI Key InChIKey=UDJALEUTCWTIEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382648   

TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50382648(CHEMBL2024001)
Affinity DataIC50: 28nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50382648(CHEMBL2024001)
Affinity DataIC50: 31nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620) expressed in SF9 cells using Biotin-Ahx- EQEDEPEGIYGVLF-OH as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed