BDBM50382664 CHEMBL2023552

SMILES COc1cc(Nc2nccc(n2)N2CCC[C@@H](C2)C(=O)N[C@@H](C)c2ccccc2)cc(OC)c1OC

InChI Key InChIKey=QFQACCUHQHRHKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382664   

TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50382664(CHEMBL2023552)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620) expressed in SF9 cells using Biotin-Ahx- EQEDEPEGIYGVLF-OH as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50382664(CHEMBL2023552)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human N-terminal GST-fused IGF1R cytoplasmic domain (960 to 1367) expressed in Hi5 cells using Biotin- Ahx- EEEEAYGWLDF-OH as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed